Charlotte Harbor Surgical · Port Charlotte & Punta Gorda, FL
Dr. John F. Guarino, MD, FACS
Board-certified general surgeon and founder of Charlotte Harbor Surgical, caring for patients in Charlotte County and Southwest Florida for more than 31 years.
Dr. Guarino specializes in gastrointestinal endoscopy and minimally invasive laparoscopic and open general surgery, providing attentive, expeditious care tailored to each patient.
- Board Certified, American Board of Surgery
- Fellow, American College of Surgeons (FACS)
- Georgetown University MD (1990) · 31+ Years Serving Charlotte County

Experienced surgical care in Charlotte County
Dr. Guarino performs colonoscopy, upper endoscopy (EGD), Barrett’s esophagus surveillance with TissueCypher® risk testing, inguinal, femoral and umbilical/epigastric hernia surgery, gallbladder removal, breast surgery, skin cancer and skin cyst removal, subcutaneous lipoma excision, abscess drainage, hemorrhoid and perirectal abscess care, temporal artery biopsy, feeding tube placement, and port (port-a-cath) placement as outpatient (same-day) procedures at Murdock Surgery Center.
Featured treatments
HemWell™ Hemorrhoid ReliefBarrett’s Esophagus & TissueCypher®MiVu™ Reflux TestingColonoscopy
A camera exam of the colon to screen for colon cancer and remove polyps.
Learn more →Upper endoscopy (EGD)
A camera exam of the esophagus, stomach and upper small intestine.
Learn more →MiVu™ reflux testing during EGD
Mucosal integrity testing for GERD, done during your upper endoscopy with no multi-day capsule to wear.
Learn more →Inguinal hernia surgery
Repair of a hernia in the groin.
Learn more →Umbilical/epigastric hernia surgery
Repair of a hernia at or near the belly button, or in the midline of the upper abdomen above it.
Learn more →Gallbladder removal
Removing the gallbladder to treat gallstones and gallbladder pain.
Learn more →Hemorrhoidal disease
Treatment for hemorrhoids that bleed, swell or cause pain.
Learn more →Barrett's esophagus surveillance & TissueCypher®
Scheduled EGD with biopsies for Barrett’s esophagus, plus risk testing on biopsy tissue already taken.
Learn more →Femoral hernia surgery
Repair of a hernia in the upper thigh, just below the groin crease.
Learn more →Breast surgery (lumpectomy, mastectomy, sentinel lymph node biopsy)
Surgery to remove breast cancer and check the nearby lymph nodes.
Learn more →Skin cancer excision
Removal of a skin cancer along with a small rim of healthy skin.
Learn more →Abscess drainage
Opening and draining a painful, infected pocket of pus under the skin.
Learn more →Skin cyst removal
Removal of a cyst that has formed under the skin.
Learn more →Perirectal abscess
Draining an infected pocket of pus near the anus or rectum.
Learn more →Temporal artery biopsy
Taking a small piece of the artery at the temple to check for inflammation of the blood vessel.
Learn more →Feeding tube placement
Placing a tube into the stomach for nutrition when a patient cannot eat enough by mouth.
Learn more →Subcutaneous lipoma excision
Removing a soft, fatty lump that has grown under the skin.
Learn more →Port placement (port-a-cath)
Placing a small implanted port under the skin for chemotherapy, IV medicines or frequent blood draws.
Learn more →About Dr. Guarino
Dr. John F. Guarino earned his undergraduate degree at St. John's University in New York, his medical degree (MD, 1990) at Georgetown University School of Medicine in Washington, D.C., and completed his general surgery residency at the State University of New York at Buffalo (1990–1995).
For more than three decades, he has led Charlotte Harbor Surgical with a commitment to personal, expeditious consultations and high-quality surgical outcomes close to home.
Where he practices
- Office
- Charlotte Harbor Surgical
4245 Kings Hwy, Unit A, Port Charlotte, FL 33980 - Hours
- Mon–Thu 7:30 am–4:00 pm
Fri 7:30 am–12:00 noon - Surgery
- Murdock Surgery Center (outpatient)
Patient reviews
Schedule a consultation with Dr. Guarino
Call Charlotte Harbor Surgical in Port Charlotte. Mon–Thu 7:30 am–4:00 pm, Fri 7:30 am–12:00 noon.