Charlotte Harbor Surgical · Port Charlotte & Punta Gorda, FL

Dr. John F. Guarino, MD, FACS

Board-certified general surgeon and founder of Charlotte Harbor Surgical, caring for patients in Charlotte County and Southwest Florida for more than 31 years.

Dr. Guarino specializes in gastrointestinal endoscopy and minimally invasive laparoscopic and open general surgery, providing attentive, expeditious care tailored to each patient.

  • Board Certified, American Board of Surgery
  • Fellow, American College of Surgeons (FACS)
  • Georgetown University MD (1990) · 31+ Years Serving Charlotte County
Dr. John F. Guarino, MD, FACS, board-certified general surgeon in Port Charlotte, FL

Experienced surgical care in Charlotte County

Dr. Guarino performs colonoscopy, upper endoscopy (EGD), Barrett’s esophagus surveillance with TissueCypher® risk testing, inguinal, femoral and umbilical/epigastric hernia surgery, gallbladder removal, breast surgery, skin cancer and skin cyst removal, subcutaneous lipoma excision, abscess drainage, hemorrhoid and perirectal abscess care, temporal artery biopsy, feeding tube placement, and port (port-a-cath) placement as outpatient (same-day) procedures at Murdock Surgery Center.

Colonoscopy

A camera exam of the colon to screen for colon cancer and remove polyps.

Learn more →

Upper endoscopy (EGD)

A camera exam of the esophagus, stomach and upper small intestine.

Learn more →

MiVu™ reflux testing during EGD

Mucosal integrity testing for GERD, done during your upper endoscopy with no multi-day capsule to wear.

Learn more →

Inguinal hernia surgery

Repair of a hernia in the groin.

Learn more →

Umbilical/epigastric hernia surgery

Repair of a hernia at or near the belly button, or in the midline of the upper abdomen above it.

Learn more →

Gallbladder removal

Removing the gallbladder to treat gallstones and gallbladder pain.

Learn more →

Hemorrhoidal disease

Treatment for hemorrhoids that bleed, swell or cause pain.

Learn more →

Barrett's esophagus surveillance & TissueCypher®

Scheduled EGD with biopsies for Barrett’s esophagus, plus risk testing on biopsy tissue already taken.

Learn more →

Femoral hernia surgery

Repair of a hernia in the upper thigh, just below the groin crease.

Learn more →

Breast surgery (lumpectomy, mastectomy, sentinel lymph node biopsy)

Surgery to remove breast cancer and check the nearby lymph nodes.

Learn more →

Skin cancer excision

Removal of a skin cancer along with a small rim of healthy skin.

Learn more →

Abscess drainage

Opening and draining a painful, infected pocket of pus under the skin.

Learn more →

Skin cyst removal

Removal of a cyst that has formed under the skin.

Learn more →

Perirectal abscess

Draining an infected pocket of pus near the anus or rectum.

Learn more →

Temporal artery biopsy

Taking a small piece of the artery at the temple to check for inflammation of the blood vessel.

Learn more →

Feeding tube placement

Placing a tube into the stomach for nutrition when a patient cannot eat enough by mouth.

Learn more →

Subcutaneous lipoma excision

Removing a soft, fatty lump that has grown under the skin.

Learn more →

Port placement (port-a-cath)

Placing a small implanted port under the skin for chemotherapy, IV medicines or frequent blood draws.

Learn more →

All procedures

About Dr. Guarino

Dr. John F. Guarino earned his undergraduate degree at St. John's University in New York, his medical degree (MD, 1990) at Georgetown University School of Medicine in Washington, D.C., and completed his general surgery residency at the State University of New York at Buffalo (1990–1995).

For more than three decades, he has led Charlotte Harbor Surgical with a commitment to personal, expeditious consultations and high-quality surgical outcomes close to home.

Read his full bio

Where he practices

Office
Charlotte Harbor Surgical
4245 Kings Hwy, Unit A, Port Charlotte, FL 33980
Hours
Mon–Thu 7:30 am–4:00 pm
Fri 7:30 am–12:00 noon
Surgery
Murdock Surgery Center (outpatient)

Directions & hours →

Patient reviews

4.5 out of 5 from 56 Google reviews (as of November 2026)

Read patient reviews on Google

Schedule a consultation with Dr. Guarino

Call Charlotte Harbor Surgical in Port Charlotte. Mon–Thu 7:30 am–4:00 pm, Fri 7:30 am–12:00 noon.

Call (941) 391-5102